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There are two ways the IOPI can be used to measure the strength of the lips. In the first method,  an IOPI bulb is placed directly between the upper and lower lip with the long axis of the IOPI bulb parallel to the lips, and then the patient/subject is asked to compress the lips as hard as possible. If the bulb is placed to the side, rather than in the midline of the lips, one may obtain a comparison of the lip strength on the two sides of the body, a measurement that might be of interest in the case of a patient with known or suspected neurological damage.

The second method involves placing the IOPI bulb under the cheek just lateral to the corner of the mouth and having the patient squeeze the IOPI bulb against the buccal surface of the teeth by pursing the lips as hard as possible.  Although this method has less face validity, I think it is valid, however, because the pressure developed in the bulb depends upon the strength of obicularis oris, the circumferential muscle complex that surrounds the mouth. It is tension in this muscle that allows the lips to be compressed against one another.

Dr. Pamela Mathy at Arizona State University has evaluated both of these methods in a group of subjects and has concluded that the second method, with the bulb in the cheek, gives more reliable measures than the first method. The trouble with the first method is that the bulb tends to roll around between the lips, and feels unstable. Subjects also unconsciously try to "trick" the measurement by folding the lips back over the teeth, which of course lets the jaws exert the pressure on the bulb.

There are currently no normal values for lip strength measured with the IOPI. I have been able to find 16 papers that have measured lip strength in normal subjects and various populations of patients. These papers can all be referenced by using the term "lip strength" to search the Pub Med database at www.NCBI.NLM.NIH.gov They have used a variety of methods, mainly strain gauge systems, but some with dynamometers and such procedures as the "button pull."  All of these methods are legitimate, but my concern is that they all involve rigid mechanical devices that can potentially cause discomfort if the lips are used with their maximal effort, and discomfort may be a limiting factor in producing a person's effort. If that is the case, one could  be measuring pain thresholds rather than strength.  The soft compliant IOPI bulb avoids this potential problem. Nevertheless, anyone interested in the topic of lip strength may find it useful to look at least some of the following references. As you may note, none of these studies has used the IOPI  to measure lip strength.

Goozee JV, Murdoch BE, and Theodoros DG. Interlabial contact pressure exhibited in dysarthria following traumatic brain injury during speech and nonspeech tasks. Folia Phoniatr. Logop. 54:177-189, 2002.
 

Entrez pubmed Results
1: Korbmacher HM, Schwan M, Berndsen S, Bull J, Kahl-Nieke B. Related Articles, Books, LinkOut
Abstract Evaluation of a new concept of myofunctional therapy in children.
Int J Orofacial Myology. 2004 Nov;30:39-52.
PMID: 15832861 [PubMed - indexed for MEDLINE]
2: Satomi M. Related Articles, Books, LinkOut
Abstract The relationship of lip strength and lip sealing in MFT.
Int J Orofacial Myology. 2001 Nov;27:18-23.
PMID: 11892367 [PubMed - indexed for MEDLINE]
3: Murdoch BE, Spencer TJ, Theodoros DG, Thompson EC. Related Articles, Books, LinkOut
Abstract Lip and tongue function in multiple sclerosis: A physiological analysis.
Motor Control. 1998 Apr;2(2):148-60.
PMID: 9644286 [PubMed - indexed for MEDLINE]
4: Thompson EC, Murdoch BE, Stokes PD. Related Articles, Books, LinkOut
Abstract Lip function in subjects with upper motor neuron type dysarthria following cerebrovascular accidents.
Eur J Disord Commun. 1995;30(4):451-66.
PMID: 8634499 [PubMed - indexed for MEDLINE]
5: McHenry MA, Minton JT, Wilson RL, Post YV. Related Articles, Books, LinkOut
Abstract Intelligibility and nonspeech orofacial strength and force control following traumatic brain injury.
J Speech Hear Res. 1994 Dec;37(6):1271-83.
PMID: 7877286 [PubMed - indexed for MEDLINE]
6: Chigira A, Omoto K, Mukai Y, Kaneko Y. Related Articles, Books, LinkOut
Abstract Lip closing pressure in disabled children: a comparison with normal children.
Dysphagia. 1994 Summer;9(3):193-8.
PMID: 7521812 [PubMed - indexed for MEDLINE]
7: Langmore SE, Lehman ME. Related Articles, Books, LinkOut
Abstract Physiologic deficits in the orofacial system underlying dysarthria in amyotrophic lateral sclerosis.
J Speech Hear Res. 1994 Feb;37(1):28-37.
PMID: 8170127 [PubMed - indexed for MEDLINE]
8: DePaul R, Brooks BR. Related Articles, Books, LinkOut
Abstract Multiple orofacial indices in amyotrophic lateral sclerosis.
J Speech Hear Res. 1993 Dec;36(6):1158-67.
PMID: 8114482 [PubMed - indexed for MEDLINE]
9: Bigenzahn W, Fischman L, Mayrhofer-Krammel U. Related Articles, Books, LinkOut
Abstract Myofunctional therapy in patients with orofacial dysfunctions affecting speech.
Folia Phoniatr (Basel). 1992;44(5):238-44.
PMID: 1490647 [PubMed - indexed for MEDLINE]
10: Thuer U, Ingervall B. Related Articles, Books, LinkOut
Abstract Effect of muscle exercise with an oral screen on lip function.
Eur J Orthod. 1990 May;12(2):198-208.
PMID: 2351205 [PubMed - indexed for MEDLINE]
11: Stranc MF, Fogel ML. Related Articles, Books, LinkOut
Abstract Lip function: a study of oral continence.
Br J Plast Surg. 1984 Oct;37(4):550-7.
PMID: 6498396 [PubMed - indexed for MEDLINE]
12: Fogel ML, Stranc MF. Related Articles, Books, LinkOut
Abstract Lip function: a study of normal lip parameters.
Br J Plast Surg. 1984 Oct;37(4):542-9.
PMID: 6498395 [PubMed - indexed for MEDLINE]
13: Janson T, Ingervall B. Related Articles, Books, LinkOut
No abstract Relationship between lip strength and lip function in posture and chewing.
Eur J Orthod. 1982 Feb;4(1):45-53. No abstract available.
PMID: 6950903 [PubMed - indexed for MEDLINE]
14: Ingervall B, Janson T. Related Articles, Books, LinkOut
Abstract The value of clinical lip strength measurements.
Am J Orthod. 1981 Nov;80(5):496-507.
PMID: 6946706 [PubMed - indexed for MEDLINE]
15: Baskervill RD. Related Articles, Books, LinkOut
No abstract Norms for obicularis oris muscular strength for normal swallowing children in grades three thru six.
Int J Oral Myol. 1977 Apr;3(2):5-7. No abstract available.
PMID: 275224 [PubMed - indexed for MEDLINE]